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A novel mechanism of inhibiting in-stent restenosis with arsenic trioxide drug-eluting stent: Enhancing contractile phenotype of vascular smooth muscle cells via YAP pathway

OBJECTIVE: Arsenic trioxide (ATO or As(2)O(3)) has beneficial effects on suppressing neointimal hyperplasia and restenosis, but the mechanism is still unclear. The goal of this study is to further understand the mechanism of ATO's inhibitory effect on vascular smooth muscle cells (VSMCs). METHO...

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Detalles Bibliográficos
Autores principales: Zhao, Yinping, Zang, Guangchao, Yin, Tieying, Ma, Xiaoyi, Zhou, Lifeng, Wu, Lingjuan, Daniel, Richard, Wang, Yunbing, Qiu, Juhui, Wang, Guixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484501/
https://www.ncbi.nlm.nih.gov/pubmed/32954055
http://dx.doi.org/10.1016/j.bioactmat.2020.08.018