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Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis
BACKGROUND: Myositis, or idiopathic inflammatory myopathy (IIM), is a group disorders of unknown etiology characterized by the inflammation of skeletal muscle. The role of T cells and their antigenic targets in IIM initiation and progression is poorly understood. T cell receptor (TCR) repertoire seq...
Autores principales: | Montagne, Janelle M., Zheng, Xuwen Alice, Pinal-Fernandez, Iago, Milisenda, Jose C., Christopher-Stine, Lisa, Lloyd, Thomas E., Mammen, Andrew L., Larman, H. Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484536/ https://www.ncbi.nlm.nih.gov/pubmed/32891935 http://dx.doi.org/10.1016/j.ebiom.2020.102972 |
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