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Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis

BACKGROUND: Myositis, or idiopathic inflammatory myopathy (IIM), is a group disorders of unknown etiology characterized by the inflammation of skeletal muscle. The role of T cells and their antigenic targets in IIM initiation and progression is poorly understood. T cell receptor (TCR) repertoire seq...

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Detalles Bibliográficos
Autores principales: Montagne, Janelle M., Zheng, Xuwen Alice, Pinal-Fernandez, Iago, Milisenda, Jose C., Christopher-Stine, Lisa, Lloyd, Thomas E., Mammen, Andrew L., Larman, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484536/
https://www.ncbi.nlm.nih.gov/pubmed/32891935
http://dx.doi.org/10.1016/j.ebiom.2020.102972

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