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Hyperconserved Elements in Human 5′UTRs Shape Essential Post-transcriptional Regulatory Networks
Post-transcriptional regulation (PTR) of gene expression is a powerful determinant of cellular phenotypes. The 5′ and 3′ untranslated regions of the mRNA (UTRs) mediate this role through sequence and secondary structure elements bound by RNA-binding proteins (RBPs) and non-coding RNAs. While functio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484617/ https://www.ncbi.nlm.nih.gov/pubmed/33005630 http://dx.doi.org/10.3389/fmolb.2020.00220 |