Multiplex detection of ctDNA mutations in plasma of colorectal cancer patients by PCR/SERS assay

Molecular diagnostic testing of KRAS and BRAF mutations has become critical in the management of colorectal cancer (CRC) patients. Some progress has been made in liquid biopsy detection of mutations in circulating tumor DNA (ctDNA), which is a fraction of circulating cell-free DNA (cfDNA), but slow...

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Detalles Bibliográficos
Autores principales: Lyu, Nana, Rajendran, Vinoth Kumar, Diefenbach, Russell J., Charles, Kellie, Clarke, Stephen J., Engel, Alexander, Rizos, Helen, Molloy, Mark P., Wang, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484630/
https://www.ncbi.nlm.nih.gov/pubmed/32923312
http://dx.doi.org/10.7150/ntno.48905

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