Cargando…

Sesamin inhibits cervical cancer cell proliferation by promoting p53/PTEN-mediated apoptosis

Background: Sesamin is a major bioactive compound in sesame seeds and has various biological properties, including anti-inflammatory and anticancer activities. Here, we explored whether sesamin activates p53, which is widely inhibited in cervical cancer cells, thereby inducing p53-mediated apoptosis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuo, Tian-Ni, Lin, Chun-Shiang, Li, Guan-De, Kuo, Cheng-Yi, Kao, Shao-Hsuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484641/ https://www.ncbi.nlm.nih.gov/pubmed/32922194 http://dx.doi.org/10.7150/ijms.48955

Ejemplares similares

Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na(+) and K(+) Currents
por: Kuo, Ping-Chung, et al.
Publicado: (2020)

Effect of miR-301a/PTEN pathway on the proliferation and apoptosis of cervical cancer
por: Peng, Li-na, et al.
Publicado: (2019)

TRIM14 promotes cell proliferation and inhibits apoptosis by suppressing PTEN in colorectal cancer
por: Shen, Weidong, et al.
Publicado: (2019)

Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model
por: Deng, Shuang, et al.
Publicado: (2018)

Sesamin Promotes Osteoblastic Differentiation and Protects Rats from Osteoporosis
por: Ma, Zhong-ping, et al.
Publicado: (2019)

Autophagy and apoptosis induction by sesamin in MOLT-4 and NB4 leukemia cells
por: Deesrisak, Kamolchanok, et al.
Publicado: (2021)

Downregulation of inhibitor of apoptosis-stimulating protein of p53 inhibits proliferation and promotes apoptosis of gastric cancer cells
por: WANG, LU-LU, et al.
Publicado: (2015)

SPAG6 promotes cell proliferation and inhibits apoptosis through the PTEN/PI3K/AKT pathway in Burkitt lymphoma
por: Zhang, Rongrong, et al.
Publicado: (2020)

Sesamin Promotes Osteoporotic Fracture Healing by Activating Chondrogenesis and Angiogenesis Pathways
por: Yang, Zhengmeng, et al.
Publicado: (2022)

Sesamin Metabolites Suppress the Induction of Cellular Senescence
por: Araki, Chie, et al.
Publicado: (2023)

TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway
por: Chen, Liuyan, et al.
Publicado: (2022)

Protective Effects of Sesamin against UVB-Induced Skin Inflammation and Photodamage In Vitro and In Vivo
por: Lin, Tzu-Yu, et al.
Publicado: (2019)

Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2
por: Huang, Bee-Piao, et al.
Publicado: (2017)

Sesamin Ameliorates Advanced Glycation End Products-Induced Pancreatic β-Cell Dysfunction and Apoptosis
por: Kong, Xiang, et al.
Publicado: (2015)

Sesamin Induces Human Leukemic Cell Apoptosis via Mitochondrial and Endoplasmic Reticulum Stress Pathways
por: Banjerdpongchai, Ratana, et al.
Publicado: (2010)

Cryptotanshinone Inhibites Bladder Cancer Cell Proliferation and Promotes Apoptosis via the PTEN/PI3K/AKT Pathway
por: Liu, Yadong, et al.
Publicado: (2020)

TRIM65 Promotes Cervical Cancer Through Selectively Degrading p53-Mediated Inhibition of Autophagy and Apoptosis
por: Wang, Xiao-Yu, et al.
Publicado: (2022)

Sesamin Acts as Anti-leukemic Compound Interacting with Novel Phosphoprotein Targets and Inducing Apoptosis in Leukemic Cells
por: Wannapruk, Pattharin, et al.
Publicado: (2022)

Antinociceptive and Anti-Inflammatory Activities of the Sesame Oil and Sesamin
por: Henriques Monteiro, Érika Maria, et al.
Publicado: (2014)

miR-92a promotes proliferation and inhibits apoptosis of prostate cancer cells through the PTEN/Akt signaling pathway
por: Yanshen, Zheng, et al.
Publicado: (2021)

Sesamin protects SH-SY5Y cells against mechanical stretch injury and promoting cell survival
por: Xu, Zhiming, et al.
Publicado: (2017)

APOBEC3B is overexpressed in cervical cancer and promotes the proliferation of cervical cancer cells through apoptosis, cell cycle, and p53 pathway
por: Wei, Zhi, et al.
Publicado: (2022)

FAM46C inhibits cell proliferation and cell cycle progression and promotes apoptosis through PTEN/AKT signaling pathway and is associated with chemosensitivity in prostate cancer
por: Ma, Libin, et al.
Publicado: (2020)

Protective Effects of the Polyphenol Sesamin on Allergen-Induced T(H)2 Responses and Airway Inflammation in Mice
por: Lin, Ching-Huei, et al.
Publicado: (2014)

Suppression of microRNA-130b inhibits glioma cell proliferation and invasion, and induces apoptosis by PTEN/AKT signaling
por: Gu, Jian-Jun, et al.
Publicado: (2018)

Promising selective MAO-B inhibition by sesamin, a lignan from Zanthoxylum flavum stems
por: Mohamed, Shaymaa M., et al.
Publicado: (2020)

Increased TCP11 gene expression can inhibit the proliferation, migration and promote apoptosis of cervical cancer cells
por: Wang, Fang, et al.
Publicado: (2023)

Silencing Of MAGI1 Promotes The Proliferation And Inhibits Apoptosis Of Glioma Cells Via The Wnt/β-Catenin And PTEN/AKT Signaling Pathways
por: Lu, Yongzhi, et al.
Publicado: (2019)

Evaluation on the combined effect of Sesamin and Schisandra extract on blood fluidity
por: Tsi, Daniel, et al.
Publicado: (2008)

Neuroprotective Effects of Sesamin and Sesamolin on Gerbil Brain in Cerebral Ischemia
por: Cheng, Fu-Chou, et al.
Publicado: (2006)

Sesamin Enhances Cholesterol Efflux in RAW264.7 Macrophages
por: Liu, Nan, et al.
Publicado: (2014)

Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction
por: Thuy, Tran Duong, et al.
Publicado: (2017)

Sesamin: A Promising Therapeutic Agent for Ameliorating Symptoms of Diabetes
por: Huang, Shu-Ming, et al.
Publicado: (2023)

EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTEN
por: Li, Zhaoming, et al.
Publicado: (2017)

Mesenchymal stem cells promote human melanocytes proliferation and resistance to apoptosis through PTEN pathway in vitiligo
por: Zhu, Lifei, et al.
Publicado: (2020)

Up-regulation of peroxiredoxin-1 promotes cell proliferation and metastasis and inhibits apoptosis in cervical cancer
por: Lu, Ermei, et al.
Publicado: (2020)

CD164 regulates proliferation and apoptosis by targeting PTEN in human glioma
por: Tu, Ming, et al.
Publicado: (2017)

MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway
por: Long, Zi-Wen, et al.
Publicado: (2018)

Human Schlafen 5 Inhibits Proliferation and Promotes Apoptosis in Lung Adenocarcinoma via the PTEN/PI3K/AKT/mTOR Pathway
por: Gu, Xuefeng, et al.
Publicado: (2021)

The Protective Effects of Sesamin against Cyclophosphamide-Induced Nephrotoxicity through Modulation of Oxidative Stress, Inflammatory-Cytokines and Apoptosis in Rats
por: Alshahrani, Saeed, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gm0t9s1atu172ho2b99cl9nlj1