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Real-time monitoring of single ZTP riboswitches reveals a complex and kinetically controlled decision landscape

RNAs begin to fold and function during transcription. Riboswitches undergo cotranscriptional switching in the context of transcription elongation, RNA folding, and ligand binding. To investigate how these processes jointly modulate the function of the folate stress-sensing Fusobacterium ulcerans ZTP...

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Detalles Bibliográficos
Autores principales: Hua, Boyang, Jones, Christopher P., Mitra, Jaba, Murray, Peter J., Rosenthal, Rebecca, Ferré-D’Amaré, Adrian R., Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484762/
https://www.ncbi.nlm.nih.gov/pubmed/32913225
http://dx.doi.org/10.1038/s41467-020-18283-1