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Real-time monitoring of single ZTP riboswitches reveals a complex and kinetically controlled decision landscape
RNAs begin to fold and function during transcription. Riboswitches undergo cotranscriptional switching in the context of transcription elongation, RNA folding, and ligand binding. To investigate how these processes jointly modulate the function of the folate stress-sensing Fusobacterium ulcerans ZTP...
Autores principales: | Hua, Boyang, Jones, Christopher P., Mitra, Jaba, Murray, Peter J., Rosenthal, Rebecca, Ferré-D’Amaré, Adrian R., Ha, Taekjip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484762/ https://www.ncbi.nlm.nih.gov/pubmed/32913225 http://dx.doi.org/10.1038/s41467-020-18283-1 |
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