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MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically
Evasion of programmed cell death represents a critical form of oncogene addiction in cancer cells. Understanding the molecular mechanisms underpinning cancer cell survival despite the oncogenic stress could provide a molecular basis for potential therapeutic interventions. Here we explore the role o...
Autores principales: | Munkhbaatar, Enkhtsetseg, Dietzen, Michelle, Agrawal, Deepti, Anton, Martina, Jesinghaus, Moritz, Boxberg, Melanie, Pfarr, Nicole, Bidola, Pidassa, Uhrig, Sebastian, Höckendorf, Ulrike, Meinhardt, Anna-Lena, Wahida, Adam, Heid, Irina, Braren, Rickmer, Mishra, Ritu, Warth, Arne, Muley, Thomas, Poh, Patrina S. P., Wang, Xin, Fröhling, Stefan, Steiger, Katja, Slotta-Huspenina, Julia, van Griensven, Martijn, Pfeiffer, Franz, Lange, Sebastian, Rad, Roland, Spella, Magda, Stathopoulos, Georgios T., Ruland, Jürgen, Bassermann, Florian, Weichert, Wilko, Strasser, Andreas, Branca, Caterina, Heikenwalder, Mathias, Swanton, Charles, McGranahan, Nicholas, Jost, Philipp J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484793/ https://www.ncbi.nlm.nih.gov/pubmed/32913197 http://dx.doi.org/10.1038/s41467-020-18372-1 |
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