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Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience

This retrospective study aimed to clarify the short-term and mid-term outcomes of and prognostic factors for patients who underwent surgical repair for uncomplicated acute type A aortic dissection (ATAAD). Between January 2007 and June 2019, 603 consecutive patients underwent ATAAD repair at our ins...

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Autores principales: Lin, Chun-Yu, See, Lai-Chu, Tseng, Chi-Nan, Wu, Meng-Yu, Han, Yi, Lu, Cheng-Hui, Tsai, Feng-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484816/
https://www.ncbi.nlm.nih.gov/pubmed/32913262
http://dx.doi.org/10.1038/s41598-020-71961-4
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author Lin, Chun-Yu
See, Lai-Chu
Tseng, Chi-Nan
Wu, Meng-Yu
Han, Yi
Lu, Cheng-Hui
Tsai, Feng-Chun
author_facet Lin, Chun-Yu
See, Lai-Chu
Tseng, Chi-Nan
Wu, Meng-Yu
Han, Yi
Lu, Cheng-Hui
Tsai, Feng-Chun
author_sort Lin, Chun-Yu
collection PubMed
description This retrospective study aimed to clarify the short-term and mid-term outcomes of and prognostic factors for patients who underwent surgical repair for uncomplicated acute type A aortic dissection (ATAAD). Between January 2007 and June 2019, 603 consecutive patients underwent ATAAD repair at our institution. According to patients’ preoperative presentations and imaging studies, uncomplicated ATAAD was found in 276 (45.8%) patients by excluding preoperative complicated factors. Patients with uncomplicated ATAAD were classified into the survivor (n = 243) and non-survivor (n = 33) groups. Clinical features, surgical information, and postoperative complications were compared. Three-year survival and freedom from reoperation rates for survivors were analyzed using the Kaplan–Meier actuarial method. The in-hospital surgical mortality rate of uncomplicated ATAAD patients was 11.9%. The non-survivor group had a higher rate of postoperative malperfusion-related complications, and a multivariate analysis revealed that repeat surgery, retrograde cerebral perfusion, and intraoperative extracorporeal membrane oxygenation support were predictors of in-hospital mortality. In the survivor group, 3-year cumulative survival and freedom from aortic reoperation rates were 89.6% (95% confidence interval [CI] 84.8–92.9%) and 83.1% (95% CI 76.8–87.7%), respectively. In conclusion, uncomplicated and complicated ATAAD rates were similar; the short-term and mid-term surgical outcomes in patients with uncomplicated ATAAD were generally acceptable.
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spelling pubmed-74848162020-09-15 Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience Lin, Chun-Yu See, Lai-Chu Tseng, Chi-Nan Wu, Meng-Yu Han, Yi Lu, Cheng-Hui Tsai, Feng-Chun Sci Rep Article This retrospective study aimed to clarify the short-term and mid-term outcomes of and prognostic factors for patients who underwent surgical repair for uncomplicated acute type A aortic dissection (ATAAD). Between January 2007 and June 2019, 603 consecutive patients underwent ATAAD repair at our institution. According to patients’ preoperative presentations and imaging studies, uncomplicated ATAAD was found in 276 (45.8%) patients by excluding preoperative complicated factors. Patients with uncomplicated ATAAD were classified into the survivor (n = 243) and non-survivor (n = 33) groups. Clinical features, surgical information, and postoperative complications were compared. Three-year survival and freedom from reoperation rates for survivors were analyzed using the Kaplan–Meier actuarial method. The in-hospital surgical mortality rate of uncomplicated ATAAD patients was 11.9%. The non-survivor group had a higher rate of postoperative malperfusion-related complications, and a multivariate analysis revealed that repeat surgery, retrograde cerebral perfusion, and intraoperative extracorporeal membrane oxygenation support were predictors of in-hospital mortality. In the survivor group, 3-year cumulative survival and freedom from aortic reoperation rates were 89.6% (95% confidence interval [CI] 84.8–92.9%) and 83.1% (95% CI 76.8–87.7%), respectively. In conclusion, uncomplicated and complicated ATAAD rates were similar; the short-term and mid-term surgical outcomes in patients with uncomplicated ATAAD were generally acceptable. Nature Publishing Group UK 2020-09-10 /pmc/articles/PMC7484816/ /pubmed/32913262 http://dx.doi.org/10.1038/s41598-020-71961-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lin, Chun-Yu
See, Lai-Chu
Tseng, Chi-Nan
Wu, Meng-Yu
Han, Yi
Lu, Cheng-Hui
Tsai, Feng-Chun
Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience
title Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience
title_full Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience
title_fullStr Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience
title_full_unstemmed Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience
title_short Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience
title_sort surgical outcomes analysis in patients with uncomplicated acute type a aortic dissection: a 13-year institutional experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484816/
https://www.ncbi.nlm.nih.gov/pubmed/32913262
http://dx.doi.org/10.1038/s41598-020-71961-4
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