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Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy

PURPOSE: The heavy‐ion medical machine (HIMM), which is the first commercial medical accelerator designed and built independently by the institute of modern physics (IMP) in Wuwei, Gansu Province, China, had officially completed clinical trials at the time of this article's writing. Three types...

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Autores principales: Wei, Kun, Xu, Zhiguo, Mao, Ruishi, Zhao, Zulong, Zhao, Tiecheng, She, Qianshun, Kang, Xincai, Wang, Jianli, Li, Shengpeng, Li, Min, Song, Kai, Yang, Herun, Duan, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484831/
https://www.ncbi.nlm.nih.gov/pubmed/32614149
http://dx.doi.org/10.1002/acm2.12916
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author Wei, Kun
Xu, Zhiguo
Mao, Ruishi
Zhao, Zulong
Zhao, Tiecheng
She, Qianshun
Kang, Xincai
Wang, Jianli
Li, Shengpeng
Li, Min
Song, Kai
Yang, Herun
Duan, Limin
author_facet Wei, Kun
Xu, Zhiguo
Mao, Ruishi
Zhao, Zulong
Zhao, Tiecheng
She, Qianshun
Kang, Xincai
Wang, Jianli
Li, Shengpeng
Li, Min
Song, Kai
Yang, Herun
Duan, Limin
author_sort Wei, Kun
collection PubMed
description PURPOSE: The heavy‐ion medical machine (HIMM), which is the first commercial medical accelerator designed and built independently by the institute of modern physics (IMP) in Wuwei, Gansu Province, China, had officially completed clinical trials at the time of this article's writing. Three types of detector systems were developed based on the ionization‐chamber principle to monitor the beam parameters during treatment in real time, quickly verify the beam performance during a routine checkup, and ensure patient safety. METHODS AND MATERIALS: The above‐mentioned detector systems were used for beam monitoring and quality assurance in the treatment system. The beam‐monitoring system is composed of three integral ionization chambers (ICs) and two multistrip ionization chambers (MSICs) as a redundant design. The irradiation dose, beam position, and homogeneity of a lateral profile are monitored online by the beam‐monitoring system, and safety interlocks are established to keep the test results under the predefined tolerance limitation. The quality‐assurance equipment was composed of one MSIC and one IC stack. The IC stack was used for energy verification. RESULTS: The off‐axis response of ICs is within a tolerance of 2%, and the dose interlock system (DIS) response time is less than 7 ms during the treatment process. The positioning resolution of MSICs reached 73 µm. The IC stack can verify the beam range within one spill and the measurement resolution is less than 0.2 mm. CONCLUSIONS: The beam‐monitoring system (BMS) and quality‐assurance equipment (QAE) have been installed and run successfully within HIMM for two years and are associated with the HIMM treatment system to deliver the right dose to the correct position precisely. Furthermore, the daily QA task is simplified by it. Above all, the system has passed the performance test of the China Food and Drug Administration (CFDA).
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spelling pubmed-74848312020-09-17 Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy Wei, Kun Xu, Zhiguo Mao, Ruishi Zhao, Zulong Zhao, Tiecheng She, Qianshun Kang, Xincai Wang, Jianli Li, Shengpeng Li, Min Song, Kai Yang, Herun Duan, Limin J Appl Clin Med Phys Radiation Measurements PURPOSE: The heavy‐ion medical machine (HIMM), which is the first commercial medical accelerator designed and built independently by the institute of modern physics (IMP) in Wuwei, Gansu Province, China, had officially completed clinical trials at the time of this article's writing. Three types of detector systems were developed based on the ionization‐chamber principle to monitor the beam parameters during treatment in real time, quickly verify the beam performance during a routine checkup, and ensure patient safety. METHODS AND MATERIALS: The above‐mentioned detector systems were used for beam monitoring and quality assurance in the treatment system. The beam‐monitoring system is composed of three integral ionization chambers (ICs) and two multistrip ionization chambers (MSICs) as a redundant design. The irradiation dose, beam position, and homogeneity of a lateral profile are monitored online by the beam‐monitoring system, and safety interlocks are established to keep the test results under the predefined tolerance limitation. The quality‐assurance equipment was composed of one MSIC and one IC stack. The IC stack was used for energy verification. RESULTS: The off‐axis response of ICs is within a tolerance of 2%, and the dose interlock system (DIS) response time is less than 7 ms during the treatment process. The positioning resolution of MSICs reached 73 µm. The IC stack can verify the beam range within one spill and the measurement resolution is less than 0.2 mm. CONCLUSIONS: The beam‐monitoring system (BMS) and quality‐assurance equipment (QAE) have been installed and run successfully within HIMM for two years and are associated with the HIMM treatment system to deliver the right dose to the correct position precisely. Furthermore, the daily QA task is simplified by it. Above all, the system has passed the performance test of the China Food and Drug Administration (CFDA). John Wiley and Sons Inc. 2020-07-02 /pmc/articles/PMC7484831/ /pubmed/32614149 http://dx.doi.org/10.1002/acm2.12916 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Measurements
Wei, Kun
Xu, Zhiguo
Mao, Ruishi
Zhao, Zulong
Zhao, Tiecheng
She, Qianshun
Kang, Xincai
Wang, Jianli
Li, Shengpeng
Li, Min
Song, Kai
Yang, Herun
Duan, Limin
Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy
title Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy
title_full Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy
title_fullStr Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy
title_full_unstemmed Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy
title_short Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon‐ion therapy
title_sort performances of the beam monitoring system and quality assurance equipment for the himm of carbon‐ion therapy
topic Radiation Measurements
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484831/
https://www.ncbi.nlm.nih.gov/pubmed/32614149
http://dx.doi.org/10.1002/acm2.12916
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