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Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation

PURPOSE: To validate the dose measurements for two total skin irradiation techniques with Monte Carlo simulation, providing more information on dose distributions, and guidance on further technique optimization. METHODS: Two total skin irradiation techniques (stand‐up and lay‐down) with different se...

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Autores principales: Li, Ruiqi, Tseng, Wenchih, Wu, Qiuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484841/
https://www.ncbi.nlm.nih.gov/pubmed/32559022
http://dx.doi.org/10.1002/acm2.12921
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author Li, Ruiqi
Tseng, Wenchih
Wu, Qiuwen
author_facet Li, Ruiqi
Tseng, Wenchih
Wu, Qiuwen
author_sort Li, Ruiqi
collection PubMed
description PURPOSE: To validate the dose measurements for two total skin irradiation techniques with Monte Carlo simulation, providing more information on dose distributions, and guidance on further technique optimization. METHODS: Two total skin irradiation techniques (stand‐up and lay‐down) with different setup were simulated and validated. The Monte Carlo simulation was primarily performed within the EGSnrc environment. Parameters of jaws, MLCs, and a customized copper (Cu) filter were first tuned to match the profiles and output measured at source‐to‐skin distance (SSD) of 100 cm where the secondary source is defined. The secondary source was rotated to simulate gantry rotation. VirtuaLinac, a cloud‐based Monte Carlo package, was used for Linac head simulation as a secondary validation. The following quantities were compared with measurements: for each field/direction at the treatment SSDs, the percent depth dose (PDD), the profiles at the depth of maximum, and the absolute dosimetric output; the composite dose distribution on cylindrical phantoms of 20 to 40 cm diameters. RESULTS: Cu filter broadened the FWHM of the electron beam by 44% and degraded the mean energy by 0.7 MeV. At SSD = 100 cm, MC calculated PDDs agreed with measured data within 2%/2 mm (except for the surface voxel) and lateral profiles agreed within 3%. At the treatment SSD, profiles and output factors of individual field matched within 4%; d(max) and R(80) of the simulated PDDs also matched with measurement within 2 mm. When all fields were combined on the cylindrical phantom, the d(max) shifted toward the surface. For lay‐down technique, the maximum x‐ray contamination at the central axis was (MC: 2.2; Measurement: 2.1)% and reduced to 0.2% at 40 cm off the central axis. CONCLUSIONS: The Monte Carlo results in general agree well with the measurement, which provides support in our commissioning procedure, as well as the full three‐dimensional dose distribution of the patient phantom.
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spelling pubmed-74848412020-09-17 Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation Li, Ruiqi Tseng, Wenchih Wu, Qiuwen J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: To validate the dose measurements for two total skin irradiation techniques with Monte Carlo simulation, providing more information on dose distributions, and guidance on further technique optimization. METHODS: Two total skin irradiation techniques (stand‐up and lay‐down) with different setup were simulated and validated. The Monte Carlo simulation was primarily performed within the EGSnrc environment. Parameters of jaws, MLCs, and a customized copper (Cu) filter were first tuned to match the profiles and output measured at source‐to‐skin distance (SSD) of 100 cm where the secondary source is defined. The secondary source was rotated to simulate gantry rotation. VirtuaLinac, a cloud‐based Monte Carlo package, was used for Linac head simulation as a secondary validation. The following quantities were compared with measurements: for each field/direction at the treatment SSDs, the percent depth dose (PDD), the profiles at the depth of maximum, and the absolute dosimetric output; the composite dose distribution on cylindrical phantoms of 20 to 40 cm diameters. RESULTS: Cu filter broadened the FWHM of the electron beam by 44% and degraded the mean energy by 0.7 MeV. At SSD = 100 cm, MC calculated PDDs agreed with measured data within 2%/2 mm (except for the surface voxel) and lateral profiles agreed within 3%. At the treatment SSD, profiles and output factors of individual field matched within 4%; d(max) and R(80) of the simulated PDDs also matched with measurement within 2 mm. When all fields were combined on the cylindrical phantom, the d(max) shifted toward the surface. For lay‐down technique, the maximum x‐ray contamination at the central axis was (MC: 2.2; Measurement: 2.1)% and reduced to 0.2% at 40 cm off the central axis. CONCLUSIONS: The Monte Carlo results in general agree well with the measurement, which provides support in our commissioning procedure, as well as the full three‐dimensional dose distribution of the patient phantom. John Wiley and Sons Inc. 2020-06-19 /pmc/articles/PMC7484841/ /pubmed/32559022 http://dx.doi.org/10.1002/acm2.12921 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Li, Ruiqi
Tseng, Wenchih
Wu, Qiuwen
Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation
title Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation
title_full Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation
title_fullStr Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation
title_full_unstemmed Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation
title_short Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation
title_sort validation of the dosimetry of total skin irradiation techniques by monte carlo simulation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484841/
https://www.ncbi.nlm.nih.gov/pubmed/32559022
http://dx.doi.org/10.1002/acm2.12921
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