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Induction of natural killer antibody-dependent cell cytotoxicity and of clinical activity of cetuximab plus avelumab in non-small cell lung cancer
BACKGROUND: Antibody-dependent cell-mediated cytotoxicity (ADCC) may mediate antitumour activity of IgG1-isotype monoclonal antibody (mAb), suggesting as potential treatment combination of IgG1-mAbs, anti-epidermal growth factor receptor cetuximab and anti-programmed death-ligand-1 avelumab. METHODS...
Autores principales: | Fasano, Morena, Della Corte, Carminia Maria, Di Liello, Raimondo, Barra, Giusi, Sparano, Francesca, Viscardi, Giuseppe, Iacovino, Maria Lucia, Paragliola, Fernando, Famiglietti, Vincenzo, Ciaramella, Vincenza, Cimmino, Flora, Capasso, Mario, Iolascon, Achille, Sforza, Vincenzo, Morabito, Alessandro, Maiello, Evaristo, Ciardiello, Fortunato, Morgillo, Floriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484864/ https://www.ncbi.nlm.nih.gov/pubmed/32912860 http://dx.doi.org/10.1136/esmoopen-2020-000753 |
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