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Diabetes mellitus is associated with elevated urinary pyrrole markers of γ-diketones known to cause axonal neuropathy
INTRODUCTION: Progressive distal symmetrical axonal neuropathy, a complication of diabetes mellitus (DM), has an unknown cause. Normal physiological metabolism and diabetic dysmetabolism are associated with the generation of γ-diketones. γ-Diketones form pyrroles with protein amines, notably with ax...
Autores principales: | Chen, Xiao, Liu, Wei, Wang, Lu, Lin, Dafeng, Nie, Lulin, He, Kaiwu, Guo, Zhiwei, Zhu, Feiqi, Feng, Wenting, Liu, Weimin, Yuan, Jing, Yang, Xifei, Spencer, Peter, Liu, Jianjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484872/ https://www.ncbi.nlm.nih.gov/pubmed/32912928 http://dx.doi.org/10.1136/bmjdrc-2020-001575 |
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