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CD8(+) tumor‐infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

OBJECTIVES: Tumor‐infiltrating lymphocytes (TIL), particularly CD8(+) TILs in patients with colorectal cancer (CRC), are highly prognostic in the early‐disease stages (I‐II). In metastatic disease (stage IV; mCRC), their influence is less well defined. It has presumably failed to contain tumor cells...

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Detalles Bibliográficos
Autores principales: Millen, Rosemary, Hendry, Shona, Narasimhan, Vignesh, Abbott, Rebecca, Croxford, Matthew, Gibbs, Peter, Tie, Jeanne, Wong, Hui‐Li, Jones, Ian, Kosmider, Suzanne, Byrne, David, Zalcberg, John, Fox, Stephen, Desai, Jayesh, Visvanathan, Kumar, Ramsay, Robert G, Tran, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484874/
https://www.ncbi.nlm.nih.gov/pubmed/32953115
http://dx.doi.org/10.1002/cti2.1155