Cargando…
The One Health Consortium: Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Combination With a Checkpoint Inhibitor in Canine Patients With Sporadic High Grade Gliomas
As the most common and deadly of primary brain tumors, malignant gliomas have earned their place within one of the most multifaceted and heavily-funded realms of medical research. Numerous avenues of pre-clinical investigation continue to provide valuable insight, but modeling the complex evolution...
Autores principales: | Chambers, M. R., Bentley, R. Timothy, Crossman, David K., Foote, Jeremy B., Koehler, Jey W., Markert, James M., Omar, Nidal B., Platt, Simon R., Self, D. Mitchell, Shores, Andy, Sorjonen, Donald C., Waters, Alicia M., Yanke, Amy B., Gillespie, G. Yancey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484881/ https://www.ncbi.nlm.nih.gov/pubmed/33005623 http://dx.doi.org/10.3389/fsurg.2020.00059 |
Ejemplares similares
-
Evaluation of immunologic parameters in canine glioma patients treated with an oncolytic herpes virus
por: Chambers, M. R., et al.
Publicado: (2021) -
Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy
por: Friedman, Gregory K., et al.
Publicado: (2013) -
Effect of HSV-IL12 Loaded Tumor Cell-Based Vaccination in a Mouse Model of High-Grade Neuroblastoma
por: Bauer, David F., et al.
Publicado: (2016) -
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants
por: Nagy, Reka, et al.
Publicado: (2017) -
γ(1)34.5-Deleted HSV-1 Expressing Human Cytomegalovirus IRS1 Gene Kills Human Glioblastoma Cells as Efficiently as Wild-type HSV-1 in Normoxia or Hypoxia
por: Friedman, Gregory K., et al.
Publicado: (2014)