MTXPK.org: A Clinical Decision Support Tool Evaluating High‐Dose Methotrexate Pharmacokinetics to Inform Post‐Infusion Care and Use of Glucarpidase

Methotrexate (MTX), an antifolate, is administered at high doses to treat malignancies in children and adults. However, there is considerable interpatient variability in clearance of high‐dose (HD) MTX. Patients with delayed clearance are at an increased risk for severe nephrotoxicity and life‐threa...

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Detalles Bibliográficos
Autores principales: Taylor, Zachary L., Mizuno, Tomoyuki, Punt, Nieko C., Baskaran, Balaji, Navarro Sainz, Adriana, Shuman, William, Felicelli, Nicholas, Vinks, Alexander A., Heldrup, Jesper, Ramsey, Laura B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484917/
https://www.ncbi.nlm.nih.gov/pubmed/32558929
http://dx.doi.org/10.1002/cpt.1957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484917/
https://www.ncbi.nlm.nih.gov/pubmed/32558929
http://dx.doi.org/10.1002/cpt.1957

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