PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses

Ataxia telangiectasia and Rad3-related protein (ATR) is a serine/threonine-protein kinase of the PI3K family and is well known for its key role in regulating DNA damage responses in the nucleus. In addition to its nuclear functions, ATR also was found to be a substrate of the prolyl isomerase Pin1 i...

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Detalles Bibliográficos
Autores principales: Makinwa, Yetunde, Cartwright, Brian M., Musich, Phillip R., Li, Zhengke, Biswas, Himadri, Zou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484947/
https://www.ncbi.nlm.nih.gov/pubmed/32984322
http://dx.doi.org/10.3389/fcell.2020.00813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484947/
https://www.ncbi.nlm.nih.gov/pubmed/32984322
http://dx.doi.org/10.3389/fcell.2020.00813

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