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The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review
In recent times, many scientists have given great attention to nutraceuticals (complementary medicine) as it widely used for promoting health status. In particular for the prevention and treatment of various neurological diseases or disorders without or less adverse effects. The current mini-review...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484964/ https://www.ncbi.nlm.nih.gov/pubmed/32953558 http://dx.doi.org/10.1016/j.jtcme.2020.03.008 |
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author | Chiu, Hui-Fang Venkatakrishnan, Kamesh Wang, Chin-Kun |
author_facet | Chiu, Hui-Fang Venkatakrishnan, Kamesh Wang, Chin-Kun |
author_sort | Chiu, Hui-Fang |
collection | PubMed |
description | In recent times, many scientists have given great attention to nutraceuticals (complementary medicine) as it widely used for promoting health status. In particular for the prevention and treatment of various neurological diseases or disorders without or less adverse effects. The current mini-review was intended to compile all popular (major) nutraceuticals against various neurodegenerative diseases (NDDs) including Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD) with special reference to clinical trials. Preliminary reviews indicated that nutraceuticals like curcumin, resveratrol, Epigallocatechin-3-gallate (EGCG), Coenzyme Q10, ω-3 FA (DHA/EPA/ALA), showed better neuroprotective activity against various NDDs in human setting (clinical trial). Hence this contribution will focus only on those popular nutraceuticals with proposed brief mechanisms (antioxidant, anti-inflammatory, mitochondrial homeostasis, autophagy regulation, promote neurogenesis) and its recommendation. This mini-review would aid common people to choose better nutraceuticals to combat various NDDs along with standard neuroprotective agents and modified lifestyle pattern. |
format | Online Article Text |
id | pubmed-7484964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-74849642020-09-17 The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review Chiu, Hui-Fang Venkatakrishnan, Kamesh Wang, Chin-Kun J Tradit Complement Med Review Article In recent times, many scientists have given great attention to nutraceuticals (complementary medicine) as it widely used for promoting health status. In particular for the prevention and treatment of various neurological diseases or disorders without or less adverse effects. The current mini-review was intended to compile all popular (major) nutraceuticals against various neurodegenerative diseases (NDDs) including Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD) with special reference to clinical trials. Preliminary reviews indicated that nutraceuticals like curcumin, resveratrol, Epigallocatechin-3-gallate (EGCG), Coenzyme Q10, ω-3 FA (DHA/EPA/ALA), showed better neuroprotective activity against various NDDs in human setting (clinical trial). Hence this contribution will focus only on those popular nutraceuticals with proposed brief mechanisms (antioxidant, anti-inflammatory, mitochondrial homeostasis, autophagy regulation, promote neurogenesis) and its recommendation. This mini-review would aid common people to choose better nutraceuticals to combat various NDDs along with standard neuroprotective agents and modified lifestyle pattern. Elsevier 2020-04-01 /pmc/articles/PMC7484964/ /pubmed/32953558 http://dx.doi.org/10.1016/j.jtcme.2020.03.008 Text en © 2020 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Chiu, Hui-Fang Venkatakrishnan, Kamesh Wang, Chin-Kun The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review |
title | The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review |
title_full | The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review |
title_fullStr | The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review |
title_full_unstemmed | The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review |
title_short | The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review |
title_sort | role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: a mini-review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484964/ https://www.ncbi.nlm.nih.gov/pubmed/32953558 http://dx.doi.org/10.1016/j.jtcme.2020.03.008 |
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