Monitoring protein-metal binding by (19)F NMR – a case study with the New Delhi metallo-β-lactamase 1

(19)F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply (19)F NMR is useful for analysis of different metallated protein states and investigations on equilibrium states in the presence of inhibi...

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Detalles Bibliográficos
Autores principales: Rydzik, Anna M., Brem, Jürgen, Chandler, Shane A., Benesch, Justin L. P., Claridge, Timothy D. W., Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484990/
https://www.ncbi.nlm.nih.gov/pubmed/33479644
http://dx.doi.org/10.1039/c9md00416e

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