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Role of Glutathione Depletion and Reactive Oxygen Species Generation on Caspase-3 Activation: A Study With the Kinase Inhibitor Staurosporine

Oxidative stress is known to contribute to the progression of apoptosis. Staurosporine is a broad-spectrum inducer of apoptosis, but its mechanism of action is not well understood. The goal of the present work was to elucidate the role of glutathione and reactive oxygen species (ROS) in the executio...

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Detalles Bibliográficos
Autores principales:	Musaogullari, Aysenur, Mandato, Alysia, Chai, Yuh-Cherng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485172/ https://www.ncbi.nlm.nih.gov/pubmed/32982774 http://dx.doi.org/10.3389/fphys.2020.00998

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