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The Antidepressant-Like Effects of Hesperidin in Streptozotocin‐Induced Diabetic Rats by Activating Nrf2/ARE/Glyoxalase 1 Pathway

The co-occurrence of diabetes and depression is a challenging and underrecognized clinical problem. Alpha-carbonyl aldehydes and their detoxifying enzyme glyoxalase 1 (Glo-1) play vital roles in the pathogenesis of diabetic complications, including depression. Hesperidin, a naturally occurring flava...

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Detalles Bibliográficos
Autores principales:	Zhu, Xia, Liu, Haiyan, Liu, Yuan, Chen, Yajing, Liu, Yaowu, Yin, Xiaoxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485173/ https://www.ncbi.nlm.nih.gov/pubmed/32982741 http://dx.doi.org/10.3389/fphar.2020.01325

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