Dysregulated Phosphorylation of p53, Autophagy and Stemness Attributes the Mutant p53 Harboring Colon Cancer Cells Impaired Sensitivity to Oxaliplatin

Colorectal cancer (CRC) forms one of the highest ranked cancer types in the world with its increasing incidence and mortality rates despite the advancement in cancer therapeutics. About 50% of human CRCs are reported to have defective p53 expression resultant of TP53 gene mutation often contributing...

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Detalles Bibliográficos
Autores principales: Therachiyil, Lubna, Haroon, Javeria, Sahir, Fairooz, Siveen, Kodappully S., Uddin, Shahab, Kulinski, Michal, Buddenkotte, Joerg, Steinhoff, Martin, Krishnankutty, Roopesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485421/
https://www.ncbi.nlm.nih.gov/pubmed/32984059
http://dx.doi.org/10.3389/fonc.2020.01744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485421/
https://www.ncbi.nlm.nih.gov/pubmed/32984059
http://dx.doi.org/10.3389/fonc.2020.01744

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