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A synthetic biosensor to detect peroxisomal acetyl-CoA concentration for compartmentalized metabolic engineering

BACKGROUND: Sub-cellular compartmentalization is used by cells to create favorable microenvironments for various metabolic reactions. These compartments concentrate enzymes, separate competing metabolic reactions, and isolate toxic intermediates. Such advantages have been recently harnessed by metab...

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Detalles Bibliográficos
Autores principales: Huttanus, Herbert M., Senger, Ryan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485502/
https://www.ncbi.nlm.nih.gov/pubmed/33194349
http://dx.doi.org/10.7717/peerj.9805