ARGX-117, a therapeutic complement inhibiting antibody targeting C2

BACKGROUND: Activation of the classical and lectin pathway of complement may contribute to tissue damage and organ dysfunction of antibody-mediated diseases and ischemia-reperfusion conditions. Complement factors are being considered as targets for therapeutic intervention. OBJECTIVE: We sought to c...

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Detalles Bibliográficos
Autores principales: Van de Walle, Inge, Silence, Karen, Budding, Kevin, Van de Ven, Liesbeth, Dijkxhoorn, Kim, de Zeeuw, Elisabeth, Yildiz, Cafer, Gabriels, Sofie, Percier, Jean-Michel, Wildemann, Johanna, Meeldijk, Jan, Simons, Peter J., Boon, Louis, Cox, Linda, Holgate, Rob, Urbanus, Rolf, Otten, Henny G., Leusen, Jeanette H.W., Blanchetot, Christophe, de Haard, Hans, Hack, C. Erik, Boross, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485568/
https://www.ncbi.nlm.nih.gov/pubmed/32926878
http://dx.doi.org/10.1016/j.jaci.2020.08.028

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