Mst1 promotes mitochondrial dysfunction and apoptosis in oxidative stress-induced rheumatoid arthritis synoviocytes

In this study, we investigated the role of macrophage stimulating 1 (Mst1) and the AMPK-Sirt1 signaling pathway in the oxidative stress-induced mitochondrial dysfunction and apoptosis seen in rheumatoid arthritis-related fibroblast-like synoviocytes (RA-FLSs). Mst1 mRNA and protein expression was si...

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Detalles Bibliográficos
Autores principales: Wang, Yingjie, Yang, Qi, Shen, Songpo, Zhang, Linjie, Xiang, Yongbo, Weng, Xisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485731/
https://www.ncbi.nlm.nih.gov/pubmed/32692720
http://dx.doi.org/10.18632/aging.103643

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