MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets

Clear-cell renal cell carcinomas (ccRCC) can be divided into four transcriptomic subtypes, two of which have a favorable and two an unfavorable prognosis. To assess mechanisms driving these subtypes, we investigated their miRNA expression patterns. miRNAs are master regulators of mRNAs, that are wid...

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Detalles Bibliográficos
Autores principales: Verbiest, Annelies, Van Hoef, Vincent, Rodriguez-Antona, Cristina, García-Donas, Jesús, Graña-Castro, Osvaldo, Albersen, Maarten, Baldewijns, Marcella, Laenen, Annouschka, Roussel, Eduard, Schöffski, Patrick, Wozniak, Agnieszka, Caruso, Stefano, Couchy, Gabrielle, Zucman-Rossi, Jessica, Beuselinck, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485767/
https://www.ncbi.nlm.nih.gov/pubmed/32915890
http://dx.doi.org/10.1371/journal.pone.0238809

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