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Investigation of gene-gene interactions in cardiac traits and serum fatty acid levels in the LURIC Health Study

Epistasis analysis elucidates the effects of gene-gene interactions (G×G) between multiple loci for complex traits. However, the large computational demands and the high multiple testing burden impede their discoveries. Here, we illustrate the utilization of two methods, main effect filtering based...

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Detalles Bibliográficos
Autores principales:	Zhou, Jiayan, Passero, Kristin, Palmiero, Nicole E., Müller-Myhsok, Bertram, Kleber, Marcus E., Maerz, Winfried, Hall, Molly A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485803/ https://www.ncbi.nlm.nih.gov/pubmed/32915819 http://dx.doi.org/10.1371/journal.pone.0238304

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