Antinociceptive effect of selective G protein-gated inwardly rectifying K(+) channel agonist ML297 in the rat spinal cord

The G protein-gated inwardly rectifying K(+) (GIRK) channels play important signaling roles in the central and peripheral nervous systems. However, the role of GIRK channel activation in pain signaling remains unknown mainly due to the lack of potent and selective GIRK channel activators until recen...

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Detalles Bibliográficos
Autores principales: Kimura, Masami, Shiokawa, Hiroaki, Karashima, Yuji, Sumie, Makoto, Hoka, Sumio, Yamaura, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485804/
https://www.ncbi.nlm.nih.gov/pubmed/32915912
http://dx.doi.org/10.1371/journal.pone.0239094

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