No QTc Prolongation With Zanubrutinib: Results of Concentration‐QTc Analysis From a Thorough QT Study in Healthy Subjects

This thorough QT (TQT) study evaluated the effect of zanubrutinib on electrocardiogram (ECG) parameters by using concentration‐QTc (C‐QTc) analysis as the primary analysis for this study. Part A of the study determined the safety and tolerability of a single supratherapeutic dose of zanubrutinib (48...

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Detalles Bibliográficos
Autores principales: Mu, Song, Darpo, Borje, Tang, Zhiyu, Novotny, William, Tawashi, Manal, Xue, Hongqi, Willett, Michael, Lin, Leo, Sahasranaman, Sri, Ou, Ying C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485941/
https://www.ncbi.nlm.nih.gov/pubmed/32144955
http://dx.doi.org/10.1111/cts.12779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485941/
https://www.ncbi.nlm.nih.gov/pubmed/32144955
http://dx.doi.org/10.1111/cts.12779

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