Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study

Determining factors that contribute to interindividual and intra‐individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans. Intestinal microbes are important contributors to variability; however, such gut microbe‐drug interactions and th...

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Detalles Bibliográficos
Autores principales: Jarmusch, Alan K., Vrbanac, Alison, Momper, Jeremiah D., Ma, Joseph D., Alhaja, Maher, Liyanage, Marlon, Knight, Rob, Dorrestein, Pieter C., Tsunoda, Shirley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485946/
https://www.ncbi.nlm.nih.gov/pubmed/32216086
http://dx.doi.org/10.1111/cts.12785

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