Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

The induction of broad and potent immunity by vaccines is the key focus of research efforts aimed at protecting against HIV-1 infection. Soluble native-like HIV-1 envelope glycoproteins have shown promise as vaccine candidates as they can induce potent autologous neutralizing responses in rabbits an...

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Detalles Bibliográficos
Autores principales: Cottrell, Christopher A., van Schooten, Jelle, Bowman, Charles A., Yuan, Meng, Oyen, David, Shin, Mia, Morpurgo, Robert, van der Woude, Patricia, van Breemen, Mariëlle, Torres, Jonathan L., Patel, Raj, Gross, Justin, Sewall, Leigh M., Copps, Jeffrey, Ozorowski, Gabriel, Nogal, Bartek, Sok, Devin, Rakasz, Eva G., Labranche, Celia, Vigdorovich, Vladimir, Christley, Scott, Carnathan, Diane G., Sather, D. Noah, Montefiori, David, Silvestri, Guido, Burton, Dennis R., Moore, John P., Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., van Gils, Marit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485981/
https://www.ncbi.nlm.nih.gov/pubmed/32866207
http://dx.doi.org/10.1371/journal.ppat.1008753

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