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Mouse tumor susceptibility genes identify drug combinations for multiple myeloma

Long-term genetic studies utilizing backcross and congenic strain analyses coupled with positional cloning strategies and functional studies identified Cdkn2a, Mtor, and Mndal as mouse plasmacytoma susceptibility/resistance genes. Tumor incidence data in congenic strains carrying the resistance alle...

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Detalles Bibliográficos
Autores principales: Zhang, Shuling, DuBois, Wendy, Zhang, Ke, Simmons, John K., Hughitt, V. Keith, Gorjifard, Sayeh, Gaikwad, Snehal, Peat, Tyler J., Mock, Beverly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486007/
https://www.ncbi.nlm.nih.gov/pubmed/32923678
http://dx.doi.org/10.20517/2394-4722.2020.40