Cargando…

Human Mesenchymal Stromal Cells Are Resistant to SARS-CoV-2 Infection under Steady-State, Inflammatory Conditions and in the Presence of SARS-CoV-2-Infected Cells

Previous studies reported on the safety and applicability of mesenchymal stem/stromal cells (MSCs) to ameliorate pulmonary inflammation in acute respiratory distress syndrome (ARDS). Thus, multiple clinical trials assessing the potential of MSCs for COVID-19 treatment are underway. Yet, as SARS-indu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schäfer, Richard, Spohn, Gabriele, Bechtel, Marco, Bojkova, Denisa, Baer, Patrick C., Kuçi, Selim, Seifried, Erhard, Ciesek, Sandra, Cinatl, Jindrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486048/ https://www.ncbi.nlm.nih.gov/pubmed/32950067 http://dx.doi.org/10.1016/j.stemcr.2020.09.003

Ejemplares similares

Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy
por: Bojkova, Denisa, et al.
Publicado: (2021)

Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication
por: Klann, Kevin, et al.
Publicado: (2020)

SARS-CoV-2 Omicron variant virus isolates are highly sensitive to interferon treatment
por: Bojkova, Denisa, et al.
Publicado: (2022)

Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings
por: Widera, Marek, et al.
Publicado: (2021)

Lack of antiviral activity of darunavir against SARS-CoV-2
por: De Meyer, Sandra, et al.
Publicado: (2020)

Aprotinin Inhibits SARS-CoV-2 Replication
por: Bojkova, Denisa, et al.
Publicado: (2020)

Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates
por: Bojkova, Denisa, et al.
Publicado: (2022)

Synergism of interferon-beta with antiviral drugs against SARS-CoV-2 variants
por: Bojkova, Denisa, et al.
Publicado: (2022)

Differentially conserved amino acid positions may reflect differences in SARS-CoV-2 and SARS-CoV behaviour
por: Bojkova, Denisa, et al.
Publicado: (2021)

Detection and infectivity of SARS-CoV-2 in exhumated corpses
por: Plenzig, S., et al.
Publicado: (2021)

In vitro activity of itraconazole against SARS‐CoV‐2
por: Van Damme, Ellen, et al.
Publicado: (2021)

SARS-CoV-2 Variants Show Different Host Cell Proteome Profiles With Delayed Immune Response Activation in Omicron-Infected Cells
por: Metzler, Melinda, et al.
Publicado: (2023)

Optimized qRT-PCR Approach for the Detection of Intra- and Extra-Cellular SARS-CoV-2 RNAs
por: Toptan, Tuna, et al.
Publicado: (2020)

Enisamium Inhibits SARS-CoV-2 RNA Synthesis
por: Elli, Stefano, et al.
Publicado: (2021)

Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China
por: Hoehl, Sebastian, et al.
Publicado: (2020)

Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants
por: Wagner, Julian U. G., et al.
Publicado: (2021)

USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING
por: Karlowitz, Rebekka, et al.
Publicado: (2022)

Characterization of ACE Inhibitors and AT(1)R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell Model
por: Reus, Philipp, et al.
Publicado: (2021)

A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection
por: Ellinger, Bernhard, et al.
Publicado: (2021)

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection
por: Mukherjee, Rukmini, et al.
Publicado: (2021)

Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection
por: de Bruin, Natasja, et al.
Publicado: (2022)

Silver N-heterocyclic carbene complexes are potent uncompetitive inhibitors of the papain-like protease with antiviral activity against SARS-CoV-2
por: Gil-Moles, Maria, et al.
Publicado: (2023)

Discovery of anti-SARS-CoV-2 secondary metabolites from the heartwood of Pterocarpus santalinus using multi-informative molecular networking
por: Wasilewicz, Andreas, et al.
Publicado: (2023)

Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform
por: Bojkova, Denisa, et al.
Publicado: (2023)

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
por: Shin, Donghyuk, et al.
Publicado: (2020)

Development and optimization of a high‐throughput screening assay for in vitro anti‐SARS‐CoV‐2 activity: Evaluation of 5676 Phase 1 Passed Structures
por: Chiu, Winston, et al.
Publicado: (2022)

SARS-CoV, MERS-CoV and SARS-CoV-2 infections in pregnancy and fetal development
por: de Souza Silva, Guilherme Antonio, et al.
Publicado: (2020)

Imaging findings in coronavirus infections: SARS-CoV, MERS-CoV, and SARS-CoV-2
por: Franquet, Tomas, et al.
Publicado: (2020)

Die Virologie von SARS-CoV-2
por: Hoehl, S., et al.
Publicado: (2020)

Die Virologie von SARS-CoV-2
por: Hoehl, S., et al.
Publicado: (2020)

Die Virologie von SARS-CoV-2
por: Hoehl, S., et al.
Publicado: (2020)

SARS-CoV-2 screening strategies for returning international travellers: Evaluation of a rapid antigen test approach
por: Layer, Emily, et al.
Publicado: (2022)

Novel multiple swab method enables high efficiency in SARS‐CoV‐2 screenings without loss of sensitivity for screening of a complete population
por: Schmidt, Michael, et al.
Publicado: (2020)

The Comparative Immunological Characteristics of SARS-CoV, MERS-CoV, and SARS-CoV-2 Coronavirus Infections
por: Zhang, Yun-yu, et al.
Publicado: (2020)

Comparison of the COVID-2019 (SARS-CoV-2) pathogenesis with SARS-CoV and MERS-CoV infections
por: Fani, Mona, et al.
Publicado: (2020)

Enisamium is an inhibitor of the SARS-CoV-2 RNA polymerase and shows improvement of recovery in COVID-19 patients in an interim analysis of a clinical trial
por: Holubovska, Olha, et al.
Publicado: (2021)

Immune Responses in SARS-CoV-2, SARS-CoV, and MERS-CoV Infections: A Comparative Review
por: Irani, Soussan
Publicado: (2022)

Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach
por: Wasilewicz, Andreas, et al.
Publicado: (2023)

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
por: Armstrong, Lee A., et al.
Publicado: (2021)

The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV
por: Hemmat, Nima, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7na6acj7mrmimt34fedusukvfc