LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium

Intestinal epithelial homeostasis is maintained by adult intestinal stem cells, which, alongside Paneth cells, appear after birth in the neonatal period. We aimed to identify regulators of neonatal intestinal epithelial development by testing a small library of epigenetic modifier inhibitors in Pane...

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Detalles Bibliográficos
Autores principales: Zwiggelaar, Rosalie T., Lindholm, Håvard T., Fosslie, Madeleine, Terndrup Pedersen, Marianne, Ohta, Yuki, Díez-Sánchez, Alberto, Martín-Alonso, Mara, Ostrop, Jenny, Matano, Mami, Parmar, Naveen, Kvaløy, Emilie, Spanjers, Roos R., Nazmi, Kamran, Rye, Morten, Drabløs, Finn, Arrowsmith, Cheryl, Arne Dahl, John, Jensen, Kim B., Sato, Toshiro, Oudhoff, Menno J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486101/
https://www.ncbi.nlm.nih.gov/pubmed/32917713
http://dx.doi.org/10.1126/sciadv.abc0367

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