β-Catenin and Associated Proteins Regulate Lineage Differentiation in Ground State Mouse Embryonic Stem Cells

Mouse embryonic stem cells (ESCs) cultured in defined medium resemble the pre-implantation epiblast in the ground state, with full developmental capacity including the germline. β-Catenin is required to maintain ground state pluripotency in mouse ESCs, but its exact role is controversial. Here, we r...

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Detalles Bibliográficos
Autores principales: Tao, Fang, Soffers, Jelly, Hu, Deqing, Chen, Shiyuan, Gao, Xin, Zhang, Ying, Zhao, Chongbei, Smith, Sarah E., Unruh, Jay R., Zhang, Da, Tsuchiya, Dai, Venkatraman, Aparna, Zhao, Meng, Li, Zhenrui, Qian, Pengxu, Parmely, Tari, He, Xi C., Washburn, Michael, Florens, Laurence, Perry, John M., Zeitlinger, Julia, Workman, Jerry, Li, Linheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486223/
https://www.ncbi.nlm.nih.gov/pubmed/32822591
http://dx.doi.org/10.1016/j.stemcr.2020.07.018

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