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Nucleolar RNA polymerase II drives ribosome biogenesis
Proteins are universally manufactured by ribosomes, which are assembled within major nuclear compartments called nucleoli(1,2). Current paradigms suggest that only RNA polymerase I and III (Pol I and Pol III) directly mediate the expression of ribosomal RNA (rRNA) components of ribosomes. Here, we s...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486236/ https://www.ncbi.nlm.nih.gov/pubmed/32669707 http://dx.doi.org/10.1038/s41586-020-2497-0 |