Nucleolar RNA polymerase II drives ribosome biogenesis

Proteins are universally manufactured by ribosomes, which are assembled within major nuclear compartments called nucleoli(1,2). Current paradigms suggest that only RNA polymerase I and III (Pol I and Pol III) directly mediate the expression of ribosomal RNA (rRNA) components of ribosomes. Here, we s...

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Detalles Bibliográficos
Autores principales: Abraham, Karan J., Khosraviani, Negin, Chan, Janet N.Y., Gorthi, Aparna, Samman, Anas, Zhao, Dorothy Y., Wang, Miling, Bokros, Michael, Vidya, Elva, Ostrowski, Lauren A., Oshidari, Roxanne, Pietrobon, Violena, Patel, Parasvi, Algouneh, Arash, Singhania, Rajat, Liu, Yupeng, Yerlici, V. Talya, De Carvalho, Daniel D., Ohh, Michael, Dickson, Brendan C., Hakem, Razq, Greenblatt, Jack F., Lee, Stephen, Bishop, Alexander J. R., Mekhail, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486236/
https://www.ncbi.nlm.nih.gov/pubmed/32669707
http://dx.doi.org/10.1038/s41586-020-2497-0

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