Convergent Evolution in Breadth of Two V(H)6-1-Encoded Influenza Antibody Clonotypes from a Single Donor

Understanding how broadly neutralizing antibodies (bnAbs) to influenza hemagglutinin (HA) naturally develop in humans is critical to the design of universal influenza vaccines. Several classes of bnAbs directed to the conserved HA stem were found in multiple individuals, including one encoded by hea...

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Detalles Bibliográficos
Autores principales: Wu, Nicholas C., Andrews, Sarah F., Raab, Julie E., O’Connell, Sarah, Schramm, Chaim A., Ding, Xintao, Chambers, Michael J., Leung, Kwanyee, Wang, Lingshu, Zhang, Yi, Mascola, John R., Douek, Daniel C., Ledgerwood, Julie E., McDermott, Adrian B., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486241/
https://www.ncbi.nlm.nih.gov/pubmed/32619441
http://dx.doi.org/10.1016/j.chom.2020.06.003

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