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Selecting appropriate endpoints for assessing treatment effects in comparative clinical studies for COVID-19

To evaluate the efficacy and safety of a new treatment for COVID-19 vs. standard care, certain key endpoints are related to the duration of a specific event, such as hospitalization, ICU stay, or receipt of supplemental oxygen. However, since patients may die in the hospital during study follow-up,...

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Detalles Bibliográficos
Autores principales: McCaw, Zachary R., Tian, Lu, Sheth, Kevin N., Hsu, Wan-Ting, Kimberly, W. Taylor, Wei, Lee-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486285/
https://www.ncbi.nlm.nih.gov/pubmed/32927092
http://dx.doi.org/10.1016/j.cct.2020.106145