JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature

• We report here a case of JC virus granule cell neuronopathy associated with Ruxolitinib; • It is worthwhile considering the possibility of JCV-GCN in myelofibrosis patients receiving ruxiolitinib, who present with progressive cerebellar symptoms and cerebellar atrophy. • Combination therapy using...

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Autores principales: Nakayama, Kentaro, Nakamura, Masataka, Konishi, Akiko, Kaneko, Satoshi, Nakamichi, Kazuo, Saijo, Masayuki, Yakushiji, Yusuke, Kusaka, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Letters to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486434/
https://www.ncbi.nlm.nih.gov/pubmed/32954021
http://dx.doi.org/10.1016/j.ensci.2020.100269
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author Nakayama, Kentaro
Nakamura, Masataka
Konishi, Akiko
Kaneko, Satoshi
Nakamichi, Kazuo
Saijo, Masayuki
Yakushiji, Yusuke
Kusaka, Hirofumi
author_facet Nakayama, Kentaro
Nakamura, Masataka
Konishi, Akiko
Kaneko, Satoshi
Nakamichi, Kazuo
Saijo, Masayuki
Yakushiji, Yusuke
Kusaka, Hirofumi
author_sort Nakayama, Kentaro
collection PubMed
description • We report here a case of JC virus granule cell neuronopathy associated with Ruxolitinib; • It is worthwhile considering the possibility of JCV-GCN in myelofibrosis patients receiving ruxiolitinib, who present with progressive cerebellar symptoms and cerebellar atrophy. • Combination therapy using mefloquine and mirtazapine may be an effective treatment.
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spelling pubmed-74864342020-09-17 JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature Nakayama, Kentaro Nakamura, Masataka Konishi, Akiko Kaneko, Satoshi Nakamichi, Kazuo Saijo, Masayuki Yakushiji, Yusuke Kusaka, Hirofumi eNeurologicalSci Letters to the Editor • We report here a case of JC virus granule cell neuronopathy associated with Ruxolitinib; • It is worthwhile considering the possibility of JCV-GCN in myelofibrosis patients receiving ruxiolitinib, who present with progressive cerebellar symptoms and cerebellar atrophy. • Combination therapy using mefloquine and mirtazapine may be an effective treatment. Elsevier 2020-09-02 /pmc/articles/PMC7486434/ /pubmed/32954021 http://dx.doi.org/10.1016/j.ensci.2020.100269 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letters to the Editor
Nakayama, Kentaro
Nakamura, Masataka
Konishi, Akiko
Kaneko, Satoshi
Nakamichi, Kazuo
Saijo, Masayuki
Yakushiji, Yusuke
Kusaka, Hirofumi
JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature
title JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature
title_full JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature
title_fullStr JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature
title_full_unstemmed JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature
title_short JC virus granule cell neuronopathy associated with Ruxolitinib: A case report and review of the literature
title_sort jc virus granule cell neuronopathy associated with ruxolitinib: a case report and review of the literature
topic Letters to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486434/
https://www.ncbi.nlm.nih.gov/pubmed/32954021
http://dx.doi.org/10.1016/j.ensci.2020.100269
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