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Phase II study of intraperitoneal submicron particle paclitaxel (SPP) plus IV carboplatin and paclitaxel in patients with epithelial ovarian cancersurgery

Submicron particles (~800 nm) of paclitaxel (SPP) contain 1–2 billion molecules of pure drug that release tumoricidal levels of paclitaxel over many weeks. This study compared two dose-levels of SPP instilled into the peritoneal cavity (IP) in 200 ml of saline post-cytoreductive surgery. Eligible pa...

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Detalles Bibliográficos
Autores principales: Mullany, Sally, Miller, David Scott, Robison, Katina, Levinson, Kimberly, Lee, Yi-Chun, Yamada, S. Diane, Walker, Joan, Markman, Maurie, Marin, Alyson, Mast, Peter, diZerega, Gere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486435/
https://www.ncbi.nlm.nih.gov/pubmed/32953961
http://dx.doi.org/10.1016/j.gore.2020.100627