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Direct Delivery of Apatite Nanoparticle-Encapsulated siRNA Targeting TIMP-1 for Intractable Abnormal Scars

Hypertrophic scars (HSs) and keloids are histologically characterized by excessive extracellular matrix (ECM) deposition. ECM deposition depends on the balance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteases (TIMPs). TIMP-1 has been linked to ECM degradation and is...

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Detalles Bibliográficos
Autores principales:	Aoki, Masayo, Matsumoto, Noriko M., Dohi, Teruyuki, Kuwahawa, Hiroaki, Akaishi, Satoshi, Okubo, Yuri, Ogawa, Rei, Yamamoto, Hirofumi, Takabe, Kazuaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486579/ https://www.ncbi.nlm.nih.gov/pubmed/32911344 http://dx.doi.org/10.1016/j.omtn.2020.08.005

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