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Lopinavir-Ritonavir in SARS-CoV-2 Infection and Drug-Drug Interactions with Cardioactive Medications

Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A low dose of ritonavir is added to other protease inhibitors to take advantage of potent inhibition of cytochrome (CYP) P450 3A4, thereby significantly increasing the plasma concentration of coadministered lopi...

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Detalles Bibliográficos
Autores principales:	Agarwal, Shubham, Agarwal, Sanjeev Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486594/ https://www.ncbi.nlm.nih.gov/pubmed/32918656 http://dx.doi.org/10.1007/s10557-020-07070-1

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