A noncanonical role of NOD-like receptor NLRP14 in PGCLC differentiation and spermatogenesis

NOD-like receptors (NLRs) are traditionally recognized as major inflammasome components. The role of NLRs in germ cell differentiation and reproduction is not known. Here, we identified the gonad-specific Nlrp14 as a pivotal regulator in primordial germ cell-like cell (PGCLC) differentiation in vitr...

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Detalles Bibliográficos
Autores principales: Yin, Yike, Cao, Shiyu, Fu, Huancheng, Fan, Xueying, Xiong, Jingfei, Huang, Qiuyue, Liu, Yu, Xie, Kun, Meng, Tie-Gang, Liu, Yuliang, Tang, Dan, Yang, Tingting, Dong, Biao, Qi, Shiqian, Nie, Ling, Zhang, Huiyuan, Hu, Hongbo, Xu, Wenming, Li, Fuping, Dai, Lunzhi, Sun, Qing-Yuan, Li, Zhonghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486727/
https://www.ncbi.nlm.nih.gov/pubmed/32839316
http://dx.doi.org/10.1073/pnas.2005533117

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