Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells

Anaplastic lymphoma kinase (Alk) is a receptor tyrosine kinase of the insulin receptor super-family that functions as oncogenic driver in a range of human cancers such as neuroblastoma. In order to investigate mechanisms underlying Alk oncogenic signaling, we conducted a genetic suppressor screen in...

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Detalles Bibliográficos
Autores principales: Wolfstetter, Georg, Pfeifer, Kathrin, Backman, Mattias, Masudi, Tafheem A., Mendoza-García, Patricia, Chen, Sa, Sonnenberg, Hannah, Sukumar, Sanjay K., Uçkun, Ezgi, Varshney, Gaurav K., Uv, Anne, Palmer, Ruth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486895/
https://www.ncbi.nlm.nih.gov/pubmed/32917927
http://dx.doi.org/10.1038/s41598-020-70890-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486895/
https://www.ncbi.nlm.nih.gov/pubmed/32917927
http://dx.doi.org/10.1038/s41598-020-70890-6

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