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Pre-pro is a fast pre-processor for single-particle cryo-EM by enhancing 2D classification

2D classification plays a pivotal role in analyzing single particle cryo-electron microscopy images. Here, we introduce a simple and loss-less pre-processor that incorporates a fast dimension-reduction (2SDR) de-noiser to enhance 2D classification. By implementing this 2SDR pre-processor prior to a...

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Detalles Bibliográficos
Autores principales: Chung, Szu-Chi, Lin, Hsin-Hung, Niu, Po-Yao, Huang, Shih-Hsin, Tu, I-Ping, Chang, Wei-Hau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486923/
https://www.ncbi.nlm.nih.gov/pubmed/32917929
http://dx.doi.org/10.1038/s42003-020-01229-0