Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis

Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction–based diagnosis, the microbiopsy outperform...

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Autores principales: Churiso, Gemechu, van Henten, Saskia, Cnops, Lieselotte, Pollmann, Julia, Melkamu, Roma, Lemma, Mulualem, Kiflie, Amare, Fikre, Helina, van Griensven, Johan, Adriaensen, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486950/
https://www.ncbi.nlm.nih.gov/pubmed/32939358
http://dx.doi.org/10.1093/ofid/ofaa364
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author Churiso, Gemechu
van Henten, Saskia
Cnops, Lieselotte
Pollmann, Julia
Melkamu, Roma
Lemma, Mulualem
Kiflie, Amare
Fikre, Helina
van Griensven, Johan
Adriaensen, Wim
author_facet Churiso, Gemechu
van Henten, Saskia
Cnops, Lieselotte
Pollmann, Julia
Melkamu, Roma
Lemma, Mulualem
Kiflie, Amare
Fikre, Helina
van Griensven, Johan
Adriaensen, Wim
author_sort Churiso, Gemechu
collection PubMed
description Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction–based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.
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spelling pubmed-74869502020-09-15 Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis Churiso, Gemechu van Henten, Saskia Cnops, Lieselotte Pollmann, Julia Melkamu, Roma Lemma, Mulualem Kiflie, Amare Fikre, Helina van Griensven, Johan Adriaensen, Wim Open Forum Infect Dis Brief Reports Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction–based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower. Oxford University Press 2020-08-17 /pmc/articles/PMC7486950/ /pubmed/32939358 http://dx.doi.org/10.1093/ofid/ofaa364 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Churiso, Gemechu
van Henten, Saskia
Cnops, Lieselotte
Pollmann, Julia
Melkamu, Roma
Lemma, Mulualem
Kiflie, Amare
Fikre, Helina
van Griensven, Johan
Adriaensen, Wim
Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
title Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
title_full Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
title_fullStr Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
title_full_unstemmed Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
title_short Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
title_sort minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486950/
https://www.ncbi.nlm.nih.gov/pubmed/32939358
http://dx.doi.org/10.1093/ofid/ofaa364
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