How to design a pre-specified statistical analysis approach to limit p-hacking in clinical trials: the Pre-SPEC framework

Results from clinical trials can be susceptible to bias if investigators choose their analysis approach after seeing trial data, as this can allow them to perform multiple analyses and then choose the method that provides the most favourable result (commonly referred to as ‘p-hacking’). Pre-specific...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C., Forbes, Gordon, Cro, Suzie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487509/
https://www.ncbi.nlm.nih.gov/pubmed/32892743
http://dx.doi.org/10.1186/s12916-020-01706-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487509/
https://www.ncbi.nlm.nih.gov/pubmed/32892743
http://dx.doi.org/10.1186/s12916-020-01706-7

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