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How to design a pre-specified statistical analysis approach to limit p-hacking in clinical trials: the Pre-SPEC framework
Results from clinical trials can be susceptible to bias if investigators choose their analysis approach after seeing trial data, as this can allow them to perform multiple analyses and then choose the method that provides the most favourable result (commonly referred to as ‘p-hacking’). Pre-specific...
Autores principales: | Kahan, Brennan C., Forbes, Gordon, Cro, Suzie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487509/ https://www.ncbi.nlm.nih.gov/pubmed/32892743 http://dx.doi.org/10.1186/s12916-020-01706-7 |
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