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Deficiency of the microglial Hv1 proton channel attenuates neuronal pyroptosis and inhibits inflammatory reaction after spinal cord injury

BACKGROUND: Spinal cord injury (SCI) causes neurological dysfunction with devastating consequences. SCI pathogenesis is accompanied by inflammasome activation and neuronal damage. But the spatial pattern and the time course of neuronal pyroptosis and apoptosis after SCI should be further elucidated....

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Detalles Bibliográficos
Autores principales:	Li, Xuefei, Yu, Zhiyuan, Zong, Weifeng, Chen, Peng, Li, Jia, Wang, Minghuan, Ding, Fengfei, Xie, Minjie, Wang, Wei, Luo, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487532/ https://www.ncbi.nlm.nih.gov/pubmed/32891159 http://dx.doi.org/10.1186/s12974-020-01942-x

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